Close Menu
Open Menu

Research Contents

A01 Physical TeamA01-3 Team TAKAHASHI

Theme- 3 髙橋班 Team TAKAHASHI

Elucidation of the neuronal underpinning of hierarchical navigation by measuring and manipulating the activity of place and grid cells

The goal of this research is to understand the neuronal underpinning of hierarchical navigation through the activity of hippocampal place cells and their relatives in the brain. By leveraging model organisms, including rats and mice, which can be used to measure and manipulate neural activity in the experimental room, we will deconstruct the behavioral diagrams based on external factors as well as internal conditions.

We will use the reconfigurable maze, which is an outcome of a previous project (Systems Science of Bio-Navigation 2016–2021), as a prototype, and develop it into an environmental χlogbot that incorporates automatic deformation and contact-free intervention, in cooperation with the A02 Cyber Team. We will develop a neurologger, also established in the previous project, which wirelessly monitors neuronal activity in the brain into a wearable logger. Then, we will elucidate the neural underpinnings of hierarchical navigation in natural environments, targeting seabirds and salmonids. Through collaboration with the A02 Cyber Team, using deep learning models including place and grid cells, we aim to achieve a comprehensive understanding of hierarchical navigation by constructing a cyber-physical system (CPS) that incorporates spatiotemporal causal inference and reinforcement learning.

Researchers A01-3 髙橋班 研究者

  • Principal Investigator Susumu Takahashi Susumu Takahashi

    Graduate School of Brain Science, Doshisha University Professor

    Research field
    Neuroscience
    Research keywords
    navigation, episodic memory, hippocampus, place cell, head direction cell
    Laboratory
    https://www.takahashilab.com

  • Co-Investigator Yuya Makiguchi Yuya Makiguchi

    College of Bioresource Sciences, Nihon University Associate Professor

    Research field
    Ecological studies on reproductive success of fishes
    Research keywords
    Fish Reproductive Ecology, Bio-logging, Salmonid fishes
    Laboratory
    http://y-makiguchi-web.main.jp/

  • Co-Investigator Kaoru Ide Kaoru Ide

    Graduate School of Brain Science, Doshisha University Assistant Professor

    Research field
    Neuroscience
    Research keywords
    navigation, episodic memory, Parkinson's disease, hippocampus, place cell
    Laboratory
    https://www.takahashilab.com

Research Contents

Back to top